When it comes to cannabis, two compounds get the most attention: THC (tetrahydrocannabinol) and CBD (cannabidiol). They’re both cannabinoids, which means they come from the cannabis plant, but their effects are very different.
For everyday users, understanding how these two compounds interact with the body is essential for choosing the right product – whether you’re seeking relaxation, relief, or simply curiosity.
Knowing the differences can help you pick what aligns with your goals, so let’s unpack them.
What is THC?
THC, short for tetrahydrocannabinol, is the most well-known cannabinoid and the main psychoactive compound in cannabis. It’s the part that makes you feel “high.”
THC works by binding the CB1 receptors in the brain, which influence your mood, coordination, memory, and perception of time.
THC is often used for pain relief, as it has shown reductions in chronic and neuropathic pain. Some chemotherapy patients also use it to control nausea, stimulate appetite, and aid in sleep. Certain THC-rich strains promote deep relaxation.
Effects and Side Effects of THC
Using THC in the form of herbs or oil is common and provides an uplifting, blissful state of euphoria. It also has a calming effect, which helps lighten physical and mental load and promote sleep. THC may enhance sensory perceptions as well, with colors looking brighter and food tasting better.
However, increased use or overconsumption has been tied to anxiety or paranoia in some users. Excessive use can also lead to dry mouth, red eyes, memory issues, and impaired coordination. Due to these side effects, it’s highly discouraged to drive or operate machinery under the influence of THC.
What Is CBD?
CBD, or cannabidiol, is the calming counterpart of THC. It doesn’t produce intoxication, which means you won’t feel high when you consume it.
Instead, CBD works indirectly with the body’s endocannabinoid system, particularly the CB2 receptors, which are linked more to the immune system and inflammation response than to brain activity.
CBD is mainly used for anxiety management, seizure treatment (FDA approved), and anti-inflammatory support. Ongoing studies suggest that it could also support brain health.
Before you decide to take cannabis for medical use, refer to the laws and regulations of your state. And if you’re in California, visiting a dispensary San Diego, CA can help connect you with experts for proper guidance.
Effects and Side Effects of CBD
CBD also offers a similar kind of calmness and relaxation, but without euphoria, compared to THC. It has anti-anxiety properties, helps reduce stress, relieves pain through anti-inflammatory effects, and improves focus in some users.
But, like THC, CBD consumption can cause dry mouth and, at higher doses, drowsiness. It may also potentially interact with certain medications.
Which One is Right for You?
THC and CBD may come from the same plant, but their effects are vastly different. THC offers the “high” and stronger medical relief, while CBD provides calmness and therapeutic benefits without intoxication. For many users, the best option is finding a ratio that balances both.
If you’re trying cannabis for the first time or experimenting with new products, don’t hesitate to ask for guidance; licensed dispensaries like Catalyst Cannabis can help you make the right choice.


